Wayne J G Hellstrom Selected Research

3- (2- (2,2- dimethylpropylsulfanyl)pyridin- 3- yl)- N- (3- hydroxycyclohexyl)acrylamide

5/2010

Exploring the potential of NO-independent stimulators and activators of soluble guanylate cyclase for the medical treatment of erectile dysfunction.

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Wayne J G Hellstrom Research Topics

Disease

96	Erectile Dysfunction 01/2022 - 11/2002
38	Penile Induration (Peyronie's Disease) 01/2021 - 07/2003
13	Infections 10/2021 - 07/2004
12	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 09/2004
10	Premature Ejaculation 01/2021 - 09/2006
10	Fibrosis (Cirrhosis) 07/2019 - 12/2003
8	Pain (Aches) 01/2021 - 01/2004
7	Hypogonadism (Hypergonadotropic Hypogonadism) 05/2019 - 04/2009
6	Congenital Abnormalities (Deformity) 09/2017 - 11/2013
6	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 05/2013 - 01/2007
5	Priapism 07/2019 - 05/2013
4	Dizziness (Lightheadedness) 09/2013 - 09/2006
4	Nausea 09/2013 - 09/2006
4	Headache (Headaches) 09/2013 - 06/2005
4	Hypertension (High Blood Pressure) 01/2013 - 02/2004
4	Lower Urinary Tract Symptoms 05/2012 - 01/2008
3	Wounds and Injuries (Trauma) 01/2021 - 10/2011
3	Urethral Stricture 01/2018 - 09/2015
3	Hyperglycemia 01/2014 - 05/2009
3	Diabetes Mellitus 03/2005 - 02/2004
2	Hematoma 04/2019 - 04/2016
2	Ganglion Cysts (Ganglion) 01/2019 - 03/2016
2	Urinary Incontinence 01/2018 - 04/2016
2	Stress Urinary Incontinence 01/2017 - 04/2016
2	Ejaculatory Dysfunction 09/2013 - 10/2006
2	Diarrhea 09/2013 - 01/2009
2	Persistent Infection 05/2013 - 05/2012
2	Pulmonary Hypertension 02/2013 - 09/2009
2	Flushing 01/2013 - 06/2005
2	Renal Insufficiency (Renal Failure) 03/2011 - 01/2010
2	Substance Withdrawal Syndrome (Withdrawal Symptoms) 01/2009 - 09/2008
1	Rheumatic Diseases (Rheumatism) 01/2022

Drug/Important Bio-Agent (IBA)

22	Microbial Collagenase (Clostridiopeptidase A)FDA Link 01/2021 - 07/2013
12	Testosterone (Sustanon)FDA Link 11/2020 - 06/2010
11	Phosphodiesterase 5 InhibitorsIBA 03/2019 - 04/2003
11	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 03/2019 - 04/2004
9	indolepropanol phosphate (IPP)IBA 01/2021 - 09/2004
9	Sildenafil Citrate (Viagra)FDA Link 03/2019 - 11/2006
9	Vardenafil Dihydrochloride (Levitra)FDA Link 02/2013 - 11/2002
7	Pharmaceutical PreparationsIBA 01/2019 - 05/2004
7	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2016 - 03/2005
5	CollagenIBA 01/2021 - 03/2003
5	avanafilIBA 09/2016 - 11/2010
4	salicylhydroxamic acid (SHAM)IBA 01/2019 - 09/2015
4	InterferonsIBA 09/2015 - 09/2005
4	rho-Associated KinasesIBA 01/2014 - 06/2004
4	dapoxetineIBA 12/2013 - 09/2006
4	Anti-Bacterial Agents (Antibiotics)IBA 05/2013 - 01/2010
4	Tadalafil (Cialis)FDA Link 02/2013 - 09/2003
4	Streptozocin (Streptozotocin)FDA Link 05/2009 - 06/2004
4	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 03/2007 - 01/2004
3	Guanosine Monophosphate (5' Guanylic Acid)IBA 01/2016 - 01/2008
3	propylene diquat (PDQ(+))IBA 08/2015 - 08/2013
3	Imatinib Mesylate (Gleevec)FDA Link 09/2013 - 10/2010
3	alfuzosin (UroXatral)FDA Link 07/2009 - 10/2006
2	Botulinum Toxins (Botulinum Toxin)IBA 01/2021 - 01/2021
2	Hormones (Hormone)IBA 05/2019 - 06/2010
2	Antihypertensive Agents (Antihypertensives)IBA 01/2019 - 02/2013
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 10/2008
2	Cocaine (Cocaine HCl)IBA 01/2019 - 08/2007
2	Therapeutic UsesIBA 05/2016 - 08/2015
2	Collagen Type I (Type I Collagen)IBA 05/2016 - 09/2015
2	Transforming Growth Factor beta (TGF-beta)IBA 05/2016 - 09/2015
2	Pioglitazone (Actos)FDA Link 03/2016 - 11/2014
2	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2016 - 12/2008
2	AndrogensIBA 02/2013 - 06/2010
2	Gentamicins (Gentamicin)FDA LinkGeneric 11/2012 - 01/2010
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 10/2011 - 10/2010
2	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 07/2010 - 12/2003
2	NG-Nitroarginine Methyl Ester (L-NAME)IBA 07/2010 - 05/2010
2	Tamsulosin (Flomax)FDA LinkGeneric 07/2009 - 10/2006
2	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2009 - 09/2006
2	Serotonin (5 Hydroxytryptamine)IBA 09/2008 - 09/2006
2	Arginine (L-Arginine)FDA Link 10/2007 - 03/2007
2	Advanced Glycation End ProductsIBA 03/2006 - 08/2004
2	Superoxides (Superoxide)IBA 03/2005 - 04/2003
1	Blood Glucose (Blood Sugar)IBA 10/2021
1	Hemoglobins (Hemoglobin)IBA 10/2021
1	mesoglycanIBA 01/2021
1	NeuropeptidesIBA 01/2021
1	Type A Botulinum Toxins (Botox)FDA Link 01/2021
1	incobotulinumtoxinA FDA Link 01/2021
1	Cyclic Nucleotide-Gated Cation ChannelsIBA 12/2020
1	IvabradineIBA 12/2020

Therapy/Procedure

44	Therapeutics 01/2022 - 12/2003
29	Penile Prosthesis (Penile Implants) 01/2022 - 07/2003
14	Prostatectomy (Retropubic Prostatectomy) 01/2019 - 03/2003
10	Intralesional Injections 10/2018 - 01/2007
6	Drug Therapy (Chemotherapy) 12/2016 - 09/2006
5	Injections 01/2021 - 01/2004
5	Penile Implantation 07/2019 - 07/2003
4	Prostheses and Implants (Prosthesis) 01/2018 - 09/2004
3	Conservative Treatment 01/2021 - 04/2016
3	Artificial Urinary Sphincter 07/2020 - 04/2016
3	Aftercare (After-Treatment) 05/2006 - 01/2004
2	Nerve Crush 03/2016 - 11/2005
2	Traction 09/2015 - 01/2015
2	Reoperation 05/2013 - 04/2013
1	Transjugular Intrahepatic Portasystemic Shunt 01/2021
1	Suburethral Slings (Tension-Free Vaginal Tape) 07/2020